BDBM135775 US10179804, Example 160::US10632171, Peptide No. 160::US8846601, 160::US9458201, 160

SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCCC(=O)NCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC1=O)C(N)=O

InChI Key InChIKey=ZLLOVWBBACAVIV-UHFFFAOYSA-N

Data  8 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 135775   

TargetMelanocortin receptor 4(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataEC50:  0.245nMpH: 7.5 T: 2°CAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
Go to US Patent

TargetMelanocyte-stimulating hormone receptor(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataEC50:  18nMpH: 7.5 T: 2°CAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  8nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  8nM ΔG°:  -11.5kcal/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  8nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  8nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  8nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent

TargetMelanocyte-stimulating hormone receptor(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  295nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
Go to US Patent

TargetMelanocyte-stimulating hormone receptor(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  295nM ΔG°:  -9.26kcal/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
Go to US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Palatin Technologies

US Patent
LigandPNGBDBM135775(US8846601, 160 | US9458201, 160 | US10179804, Exam...)
Affinity DataKi:  295nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent