BDBM13550 3-(3,4,5-Trimethoxyphenyl)-N-(6-oxo-6-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)-hexyl)propanamide::N-[5-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)pentyl]-3-(3,4,5-trimethoxyphenyl)propanamide::tacrine derivative 16f

SMILES COc1cc(CCC(=O)NCCCCCC(=O)NNc2c3CCCCc3nc3ccccc23)cc(OC)c1OC

InChI Key InChIKey=HZEYALYZZKPABJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13550   

TargetAcetylcholinesterase(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13550(3-(3,4,5-Trimethoxyphenyl)-N-(6-oxo-6-(2-(1,2,3,4-...)
Affinity DataIC50: 8.39nMpH: 7.3 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetCholinesterase(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13550(3-(3,4,5-Trimethoxyphenyl)-N-(6-oxo-6-(2-(1,2,3,4-...)
Affinity DataIC50: 0.141nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13550(3-(3,4,5-Trimethoxyphenyl)-N-(6-oxo-6-(2-(1,2,3,4-...)
Affinity DataIC50: 39.8nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13550(3-(3,4,5-Trimethoxyphenyl)-N-(6-oxo-6-(2-(1,2,3,4-...)
Affinity DataIC50: 20.2nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed