BDBM13516 (5R)-1-[(3R)-3-amino-4-(2,5-difluorophenyl)butanoyl]-5-methylimidazolidin-4-one::Imidazolone Analog 15

SMILES C[C@H]1N(CNC1=O)C(=O)C[C@H](N)Cc1cc(F)ccc1F

InChI Key InChIKey=JQBDRMJOGLRKIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13516   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM13516((5R)-1-[(3R)-3-amino-4-(2,5-difluorophenyl)butanoy...)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed