BDBM134525 US8846656, 22-C

SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(cnc2[nH]ccc12)C(F)(F)F

InChI Key InChIKey=ROCAJYBCXJBSEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134525   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Novartis

US Patent
LigandPNGBDBM134525(US8846656, 22-C)
Affinity DataIC50: 2nMAssay Description:Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
Go to US Patent