BDBM134271 US8846660, 53

SMILES COc1ccc(Cl)cc1CC1CN\C(CN(C(=O)NCc2ccc(C(O)=O)c(N)c2)C1=O)=N/Oc1cc(F)cc(F)c1

InChI Key InChIKey=HKBSZXIBATXCQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134271   

TargetChymase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM134271(US8846660, 53)
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent