BDBM134257 US8846660, 20

SMILES CCC[C@@H](NC(=O)N1C\C(NCC(Cc2cc(Cl)ccc2OC)C1=O)=N\OCC(F)(F)F)c1ccc(C(O)=O)c(N)c1

InChI Key InChIKey=JXDJEIOLMCXLMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134257   

TargetChymase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM134257(US8846660, 20)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent