BDBM134114 US8846689, 116

SMILES CON1Cc2cccc(Oc3nc(Nc4cc(F)c(cc4OC)C(=O)N[C@@H]4CCCN(C)C4)ncc3C(F)(F)F)c2C1=O

InChI Key InChIKey=VSHQPEPVKWZJFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134114   

TargetFocal adhesion kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM134114(US8846689, 116)
Affinity DataIC50: 1nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent