BDBM133839 US8846699, 159::US8846699, 164

SMILES C[C@H](COc1cc2ncnc(Nc3ccc(Br)c(Cl)c3F)c2cc1NC(=O)C=C)NC(=O)CN(C)C

InChI Key InChIKey=GRBIBILPWGFKCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 133839   

TargetVascular endothelial growth factor receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133839(US8846699, 164 | US8846699, 159)
Affinity DataIC50: 419nMpH: 7.4 T: 2°CAssay Description:VEGFR2 (KDR, Proquinase) enzyme assay (auto-phosphorylation assay) was carried out by using Tyrosine Kinase Assay Kit Green (Panvera). The entire ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133839(US8846699, 164 | US8846699, 159)
Affinity DataIC50: 713nMpH: 7.4 T: 2°CAssay Description:VEGFR2 (KDR, Proquinase) enzyme assay (auto-phosphorylation assay) was carried out by using Tyrosine Kinase Assay Kit Green (Panvera). The entire ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133839(US8846699, 164 | US8846699, 159)
Affinity DataIC50: 286nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133839(US8846699, 164 | US8846699, 159)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent