BDBM133694 US8846699, 10

SMILES CN(C)CC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1

InChI Key InChIKey=RIFKDQITWFTYJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133694   

TargetVascular endothelial growth factor receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133694(US8846699, 10)
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:VEGFR2 (KDR, Proquinase) enzyme assay (auto-phosphorylation assay) was carried out by using Tyrosine Kinase Assay Kit Green (Panvera). The entire ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133694(US8846699, 10)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent