BDBM133689 US8846699, 5

SMILES Fc1cc(Br)ccc1Nc1ncnc2cc(OCC3CCN(CC3)C(=O)C=C)c(NC(=O)C=C)cc12

InChI Key InChIKey=VZMZAYAKDHWCNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133689   

TargetVascular endothelial growth factor receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133689(US8846699, 5)
Affinity DataIC50: 203nMpH: 7.4 T: 2°CAssay Description:VEGFR2 (KDR, Proquinase) enzyme assay (auto-phosphorylation assay) was carried out by using Tyrosine Kinase Assay Kit Green (Panvera). The entire ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM133689(US8846699, 5)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
Go to US Patent