BDBM133676 US8846711, 20::US9051321, 20

SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CC(C1)OCc1nccs1

InChI Key InChIKey=KISSQSDZTGAZSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133676   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Fab Pharma

US Patent
LigandPNGBDBM133676(US8846711, 20 | US9051321, 20)
Affinity DataIC50: 57nMpH: 6.5 T: 2°CAssay Description:Compound inhibitory activity of FabI enzyme is measured in vitro by the IC5 so determination using a fluorescence based assay.The protein FabI from S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
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TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Fab Pharma

US Patent
LigandPNGBDBM133676(US8846711, 20 | US9051321, 20)
Affinity DataIC50: 57nMpH: 6.5 T: 2°CAssay Description:The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent