BDBM13355 6-N-(2-chloro-6-methylphenyl)-2-N-cyclopropane-1,3-benzothiazole-2,6-dicarboxamide::CHEMBL67758::benzothiazole analog 11

SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)C3CC3)sc2c1

InChI Key InChIKey=TWKVMAOWCHQYRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13355   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

LigandPNGBDBM13355(CHEMBL67758 | 6-N-(2-chloro-6-methylphenyl)-2-N-cy...)
Affinity DataIC50: 9nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

LigandPNGBDBM13355(CHEMBL67758 | 6-N-(2-chloro-6-methylphenyl)-2-N-cy...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of phosphorylation of an exogenous substrate by human p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed