BDBM13305 4-Amino-3-[3-(S)-(5-isoxazol-3-ylthiophene-2-ylsulfonylamino)-2-oxopyrrolidin-1-ylmethyl]benzamidine::4-amino-3-{[(3S)-3-{[5-(1,2-oxazol-3-yl)thiophene-2-]sulfonamido}-2-oxopyrrolidin-1-yl]methyl}benzene-1-carboximidamide::Sulfonamidopyrrolidinone 4d

SMILES NC(=N)c1ccc(N)c(CN2CC[C@H](NS(=O)(=O)c3ccc(s3)-c3ccon3)C2=O)c1

InChI Key InChIKey=JZYCCVRLQKHTCR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13305   

TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13305(4-Amino-3-[3-(S)-(5-isoxazol-3-ylthiophene-2-ylsul...)
Affinity DataKi:  7nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13305(4-Amino-3-[3-(S)-(5-isoxazol-3-ylthiophene-2-ylsul...)
Affinity DataKi:  1.70E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed