BDBM13288 Sulfonamidopyrrolidinone 27::methyl 2-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}phenoxy)acetate::{4-(Aminoiminomethyl)-2-[3-(S)-(7-methoxynaphthalen-2-ylsulfonylamino)-2-oxopyrrolidin-1-ylmethyl]phenoxy}acetic Acid Methyl Ester

SMILES COC(=O)COc1ccc(cc1CN1CC[C@H](NS(=O)(=O)c2ccc3ccc(OC)cc3c2)C1=O)C(N)=N

InChI Key InChIKey=HHGGWCFPUIXQJD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13288   

TargetCoagulation factor X(Human)
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13288(methyl 2-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxyna...)
Affinity DataKi:  7.94nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13288(methyl 2-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxyna...)
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13288(methyl 2-(4-carbamimidoyl-2-{[(3S)-3-[(7-methoxyna...)
Affinity DataKi:  12nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed