BDBM132691 US8841312, 441

SMILES C[C@@H](O)CNC1CCN(CC1)c1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nn1

InChI Key InChIKey=SKRUYIPFBIYOHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132691   

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandPNGBDBM132691(US8841312, 441)
Affinity DataIC50: 3.80nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandPNGBDBM132691(US8841312, 441)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent