BDBM13253 5-N-(2-chloro-6-methylphenyl)-2-N-(furan-2-)-1,3-thiazole-2,5-diamido::BMS-354825 2-Carboxamido-4-hydrido-thiazole Analog 7u::CHEMBL128070::N-(2-Chloro-6-methylphenyl)-2-[(2-furanylcarbonyl)amino]-1,3-thiazole-5-carboxamide

SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccco2)s1

InChI Key InChIKey=BFSDCMXBRNMKDG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13253   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

LigandPNGBDBM13253(N-(2-Chloro-6-methylphenyl)-2-[(2-furanylcarbonyl)...)
Affinity DataAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

LigandPNGBDBM13253(N-(2-Chloro-6-methylphenyl)-2-[(2-furanylcarbonyl)...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CD3/CD28 T-cell proliferation assay in PBL (peripheral blood lymphocytes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed