BDBM132315 US8841312, 61

SMILES C[C@@H]1CN(CCN1)c1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nc1

InChI Key InChIKey=CUXUPHRVKKHTFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132315   

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandPNGBDBM132315(US8841312, 61)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent