BDBM13225 2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-phenyl-1,3-thiazole-5-carboxamide::BMS-354825 tert-Butoxycarbamate Analog 5f::CHEMBL424450::tert-butyl N-[4-methyl-5-(phenylcarbamoyl)-1,3-thiazol-2-yl]carbamate

SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1ccccc1

InChI Key InChIKey=ICOPXDXFUPQJCR-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13225   

TargetProto-oncogene tyrosine-protein kinase LCK(Mouse)
Bristol-Myers Squibb

LigandPNGBDBM13225(CHEMBL424450 | 2-[[(tert-Butyloxy)carbonyl]-amino]...)
Affinity DatapH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase LCK(Mouse)
Bristol-Myers Squibb

LigandPNGBDBM13225(CHEMBL424450 | 2-[[(tert-Butyloxy)carbonyl]-amino]...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed