BDBM13194 (2S)-2-amino-N-{5-benzyl-4-[(benzyloxy)methyl]-1,3-thiazol-2-yl}propanamide::SMAC mimetic compound 20k

SMILES C[C@H](N)C(=O)Nc1nc(COCc2ccccc2)c(Cc2ccccc2)s1

InChI Key InChIKey=YBRWIUWQAJGHRM-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13194   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Abbott Laboratories

LigandPNGBDBM13194((2S)-2-amino-N-{5-benzyl-4-[(benzyloxy)methyl]-1,3...)
Affinity DataKd:  4.10E+3nMAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2007
Entry Details Article
PubMed