BDBM131878 US8835444, 5.11

SMILES COc1cc(C)nn1C[C@H]1CC[C@@H](CC1)NC(=O)c1cc(ccc1Cl)C(F)(F)F

InChI Key InChIKey=KJEKFLMCRQCNRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131878   

TargetCorticotropin-releasing factor receptor 1(Human)
Novartis

US Patent
LigandPNGBDBM131878(US8835444, 5.11)
Affinity DataIC50: 67nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent