BDBM131850 US8835445, 32

SMILES COC(=O)c1ccc2n(c(nc2c1)-c1nccs1)-c1ccc2c(N)nc(N)nc2c1

InChI Key InChIKey=MLRYLGRISSFLSZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131850   

TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131850(US8835445, 32)
Affinity DataKi:  0.0210nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

TargetDihydrofolate reductase(Human)
Trius Therapeutics

US Patent
LigandPNGBDBM131850(US8835445, 32)
Affinity DataKi:  53.1nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent