BDBM131814 US8835464, 16b::US9206162, 16b

SMILES CC(N)C(=O)Oc1cc(OC(=O)C(C)N)c(cc1C(C)C)-c1nn(C(=O)C(C)N)c(=O)n1-c1ccc2n(C)ccc2c1

InChI Key InChIKey=HGDRQWHUKHHRQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131814   

TargetHeat shock protein HSP 90-beta(Human)
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131814(US8835464, 16b | US9206162, 16b)
Affinity DataIC50: 56nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131814(US8835464, 16b | US9206162, 16b)
Affinity DataIC50: 56nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
Go to US Patent