BDBM131813 US8835464, 15b::US9206162, 15b

SMILES CC(C)c1cc(-c2nn(C(=O)CN)c(=O)n2-c2ccc3n(C)ccc3c2)c(OC(=O)CN)cc1OC(=O)CN

InChI Key InChIKey=RIMCGMJQUOVYLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131813   

TargetHeat shock protein HSP 90-beta(Human)
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131813(US8835464, 15b | US9206162, 15b)
Affinity DataIC50: 79nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131813(US8835464, 15b | US9206162, 15b)
Affinity DataIC50: 79nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
Go to US Patent