BDBM13118 (2S)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxypropanamide::CGS 27023A Analog 50::CHEMBL314204

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@@H](C)C(=O)NO

InChI Key InChIKey=JRCGNOYYZQLNTH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13118   

TargetMacrophage metalloelastase(Mouse)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13118(CHEMBL314204 | (2S)-2-[benzyl(4-methoxybenzene)sul...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM13118(CHEMBL314204 | (2S)-2-[benzyl(4-methoxybenzene)sul...)
Affinity DataKi:  141nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed