BDBM13104 2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfonamido}-N-hydroxyacetamide::CGS 27023A Analog 32

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(Cl)cc1

InChI Key InChIKey=HBPRCALADDGDIK-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13104   

TargetMatrix metalloproteinase-9(Human)
Fibrogen

Curated by ChEMBL
LigandPNGBDBM13104(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)
Affinity DataIC50: 50nMAssay Description:Inhibition of para-amino phenylmercuric acetate-activated MMP9 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Fibrogen

Curated by ChEMBL
LigandPNGBDBM13104(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)
Affinity DataIC50: 140nMAssay Description:Inhibition of para-amino phenylmercuric acetate-activated MMP2 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Fibrogen

Curated by ChEMBL
LigandPNGBDBM13104(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM13104(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)
Affinity DataKi:  94nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed