BDBM13095 CGS 27023A Analog 23::N-hydroxy-2-[(4-methoxybenzene)(2-phenylethyl)sulfonamido]acetamide

SMILES COc1ccc(cc1)S(=O)(=O)N(CCc1ccccc1)CC(=O)NO

InChI Key InChIKey=HYKIXGPXDGBTKU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13095   

TargetBone morphogenetic protein 1(Human)
Fibrogen

Curated by ChEMBL
LigandPNGBDBM13095(N-hydroxy-2-[(4-methoxybenzene)(2-phenylethyl)sulf...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMeprin A subunit beta(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM13095(N-hydroxy-2-[(4-methoxybenzene)(2-phenylethyl)sulf...)
Affinity DataIC50: 4.29E+4nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM13095(N-hydroxy-2-[(4-methoxybenzene)(2-phenylethyl)sulf...)
Affinity DataKi:  66nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed