BDBM130916 US8822500, [14]

SMILES COC1N(C(=O)c2cc3nc([nH]c3cc12)-c1c(NC(C)Cc2c(F)c(F)cc(F)c2F)cc[nH]c1=O)c1cccnc1

InChI Key InChIKey=MSDSJOCXJMWGST-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 130916   

TargetHigh affinity nerve growth factor receptor(Human)
Chembridge

US Patent
LigandPNGBDBM130916(US8822500, [14])
Affinity DataIC50: 41.6nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Chembridge

US Patent
LigandPNGBDBM130916(US8822500, [14])
Affinity DataIC50: 174nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Chembridge

US Patent
LigandPNGBDBM130916(US8822500, [14])
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent