BDBM1309 3-Aminopyridin-2(1H)-one analogue 29::5-ethyl-6-methyl-3-{[(4-methyl-1,3-benzoxazol-2-yl)methyl]amino}-1,2-dihydropyridin-2-one::Pyridinone deriv. 11

SMILES CCc1cc(NCc2nc3c(C)cccc3o2)c(=O)[nH]c1C

InChI Key InChIKey=CSXPXSCMDHDMQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1309   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1309(Pyridinone deriv. 11 | 5-ethyl-6-methyl-3-{[(4-met...)
Affinity DataIC50: 120nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1309(Pyridinone deriv. 11 | 5-ethyl-6-methyl-3-{[(4-met...)
Affinity DataIC50: 125nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2004
Entry Details Article
PubMed