BDBM130438 US8822505, 40

SMILES C[C@H](Oc1ccc(c(Cl)c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CN(C)C1)c1ncc(Br)cc1F)C(=O)NC1(CC1)C#N)C(F)(F)F

InChI Key InChIKey=VJIQEIGIVWRYOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130438   

TargetProcathepsin L(Human)
Genentech

US Patent
LigandPNGBDBM130438(US8822505, 40)
Affinity DataIC50: 16.6nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
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TargetCathepsin S(Human)
Genentech

US Patent
LigandPNGBDBM130438(US8822505, 40)
Affinity DataIC50: 2.13nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent