BDBM130412 US8822505, 12

SMILES Fc1cc(Cl)cnc1C1(CNC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl

InChI Key InChIKey=KBOFMZZQYJBQLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130412   

TargetProcathepsin L(Human)
Genentech

US Patent
LigandPNGBDBM130412(US8822505, 12)
Affinity DataIC50: 23.6nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
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TargetCathepsin S(Human)
Genentech

US Patent
LigandPNGBDBM130412(US8822505, 12)
Affinity DataIC50: 1.07nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent