BDBM130401 US8822505, 1

SMILES COc1ccc(c(Cl)c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CN(C1)C(=O)OC(C)(C)C)c1ccc(Cl)cn1)C(=O)NC1(CC1)C#N

InChI Key InChIKey=STJXLOPJMMJYPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130401   

TargetProcathepsin L(Human)
Genentech

US Patent
LigandPNGBDBM130401(US8822505, 1)
Affinity DataIC50: 1.07E+3nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
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TargetCathepsin S(Human)
Genentech

US Patent
LigandPNGBDBM130401(US8822505, 1)
Affinity DataIC50: 3.22nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent