BDBM130377 N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(cyclohexylmethyl)pyridine-2- carboxamide (3)

SMILES CS(=O)(=O)NC(=O)c1ccc(c(c1)Cc2ccccc2)NC(=O)c3cccc(n3)CC4CCCCC4

InChI Key InChIKey=ZNGZJFRXFZQBMG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 130377   

TargetProtein UL24 homolog(HHV-8)
University of California San Francisco

LigandPNGBDBM130377(N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(...)
Affinity DataIC50: 3.70E+3nMpH: 8.0Assay Description:Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetCapsid scaffolding protein(HHV-5)
University of California San Francisco

LigandPNGBDBM130377(N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(...)
Affinity DataIC50: 3.90E+4nMpH: 8.0Assay Description:Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetEpstein-Barr nuclear antigen 1(HHV-4)
University of California San Francisco

LigandPNGBDBM130377(N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(...)
Affinity DataIC50: 1.90E+4nMpH: 8.0Assay Description:Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed