BDBM130241 US8815854, 42

SMILES CN(C)C(=O)c1cccc(c1)-c1ccc2nc(-c3ccccc3)n(-c3ccc(cc3)C3(N)CCC3)c2n1

InChI Key InChIKey=WOUGLXJNCVQYLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130241   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM130241(US8815854, 42)
Affinity DataIC50: 4.27nMpH: 8.0Assay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
Go to US Patent