BDBM130235 US8815854, 31

SMILES NC1(CCC1)c1ccc(cc1)-n1c(nc2ccc(nc12)-c1cccc(c1)N1CCOCC1)-c1cccc(F)c1

InChI Key InChIKey=VQEGLCNRTWJNCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130235   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM130235(US8815854, 31)
Affinity DataIC50: 35.5nMpH: 8.0Assay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
Go to US Patent