BDBM130219 US8815854, 5

SMILES COC(=O)c1ccccc1-c1nc2ccc(nc2n1-c1ccc(cc1)C1(N)CCC1)-c1cccc(c1)N1CCOCC1

InChI Key InChIKey=GQXFQHCPDRKRPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130219   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM130219(US8815854, 5)
Affinity DataIC50: 12.6nMpH: 8.0Assay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
Go to US Patent