BDBM129522 US8802673, 164

SMILES C1CO[C@@H](CN1)c1ccc(Nc2ccn(n2)-c2ccccc2)cc1

InChI Key InChIKey=YTCKKVSPGMGACJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 129522   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM129522(US8802673, 164)
Affinity DataKi:  0.600nM ΔG°:  -13.1kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 7b(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM129522(US8802673, 164)
Affinity DataKi:  25nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
Go to US Patent