BDBM12872 1-(3-amino-1,2-benzoxazol-5-yl)-6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-3-(trifluoromethyl)-1H,4H,7H-pyrazolo[4,3-b]pyridin-7-one::pyrazolo[4,3-b]pyridinone 26d

SMILES CN(C)Cc1ccccc1-c1ccc(cc1)-c1cnc2c(nn(-c3ccc4onc(N)c4c3)c2c1O)C(F)(F)F

InChI Key InChIKey=MHUDSSWPYCLMLR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12872   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12872(1-(3-amino-1,2-benzoxazol-5-yl)-6-(4-{2-[(dimethyl...)
Affinity DataKi:  3.20nM ΔG°:  -11.5kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2007
Entry Details Article
PubMed