BDBM12865 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-(2-{[(cyclopropylmethyl)amino]methyl}phenyl)phenyl]-5-methyl-3-(trifluoromethyl)-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one::Pyrazolo[4,3-d]pyrimidinone 23c

SMILES Cc1nc2c(nn(-c3ccc4onc(N)c4c3)c2c(=O)n1-c1ccc(cc1)-c1ccccc1CNCC1CC1)C(F)(F)F

InChI Key InChIKey=IMHADQMMGOEFNC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12865   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12865(1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-(2-{[(cyclopr...)
Affinity DataKi:  0.5nM ΔG°:  -12.6kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2007
Entry Details Article
PubMed