BDBM12859 1-(3-amino-1,2-benzoxazol-5-yl)-3-methyl-6-(4-{2-[(propan-2-ylamino)methyl]phenyl}phenyl)-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one::Pyrazolo[4,3-d]pyrimidinone 19e

SMILES CC(C)NCc1ccccc1-c1ccc(cc1)-n1cnc2c(C)nn(-c3ccc4onc(N)c4c3)c2c1=O

InChI Key InChIKey=FPAAVCQGCYUBJA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12859   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12859(1-(3-amino-1,2-benzoxazol-5-yl)-3-methyl-6-(4-{2-[...)
Affinity DataKi:  1.5nM ΔG°:  -11.9kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2007
Entry Details Article
PubMed