BDBM128468 US8796244, 47

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(ccn12)-c1cnn(c1)C1CCOC1

InChI Key InChIKey=VXGJUTSAHAFGCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128468   

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM128468(US8796244, 47)
Affinity DataIC50: 0.542nMpH: 8.0 T: 2°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM128468(US8796244, 47)
Affinity DataIC50: 15.5nMpH: 8.0 T: 2°CAssay Description:VEGFR2 (from Upstate), prepared at 2x final concentration, was incubated with test compounds, biotinylated Flt3 substrate (biotin-VASSDNEYFYVDF) (Cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent