BDBM128346 US8796280, 36

SMILES FC(F)(F)c1ccccc1S(=O)(=O)Nc1nccnc1-c1ccc(CN2CCc3ccccc23)cc1

InChI Key InChIKey=CUGRVWOJFYHAGN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128346   

TargetProstaglandin D2 receptor 2(Human)
Merck Serono

US Patent
LigandPNGBDBM128346(US8796280, 36)
Affinity DataKi:  2.69E+3nM ΔG°:  -7.59kcal/molepH: 7.4 T: 2°CAssay Description:The compounds of the present invention inhibit the binding of PGD2 to its receptor CRTH2. The inhibitory activity can be investigated by a radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent