BDBM128294 US8796293, 30

SMILES NCC1(CCN(CC1)c1ncnc2[nH]ccc12)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=DWJDGCPTSJEFPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128294   

TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM128294(US8796293, 30)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent