BDBM128010 US8796310, 29B

SMILES COc1ccnc(Nc2cc(C)cc(n2)-c2cnc(s2)[C@]2(O)CCCc3cc(ccc23)C(O)=O)c1

InChI Key InChIKey=PLNKGQHICRZXGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128010   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM128010(US8796310, 29B)
Affinity DataIC50: 0.600nMpH: 7.5Assay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Cama Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent