BDBM12787 3-(4-aminophenyl)-N-[4-(1H-1,3-benzodiazol-1-yl)phenyl]-2-(5-carbamimidoyl-1H-indol-3-yl)propanamide::5-amidinoindole 21::amidinoindole 22

SMILES NC(=N)c1ccc2[nH]cc(C(Cc3ccc(N)cc3)C(=O)Nc3ccc(cc3)-n3cnc4ccccc34)c2c1

InChI Key InChIKey=SAOAIXOGVSHQNA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12787   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12787(3-(4-aminophenyl)-N-[4-(1H-1,3-benzodiazol-1-yl)ph...)
Affinity DataKi:  4nM ΔG°:  -11.3kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12787(3-(4-aminophenyl)-N-[4-(1H-1,3-benzodiazol-1-yl)ph...)
Affinity DataKi:  4nM ΔG°:  -11.3kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

LigandPNGBDBM12787(3-(4-aminophenyl)-N-[4-(1H-1,3-benzodiazol-1-yl)ph...)
Affinity DataKi:  75nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

LigandPNGBDBM12787(3-(4-aminophenyl)-N-[4-(1H-1,3-benzodiazol-1-yl)ph...)
Affinity DataKi:  75nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed