BDBM127682 US8791123, 55::US8791123, 56

SMILES OCC(O)CNC(=O)c1cnn2ccc(nc12)N1CCCC1c1cc(F)ccc1CO

InChI Key InChIKey=LJJBCTSKXBRDPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 127682   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM127682(US8791123, 56 | US8791123, 55)
Affinity DataIC50: 1nMpH: 7.5Assay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM127682(US8791123, 56 | US8791123, 55)
Affinity DataIC50: 2.40nMpH: 7.5Assay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandPNGBDBM127682(US8791123, 56 | US8791123, 55)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Array Biopharma

US Patent
LigandPNGBDBM127682(US8791123, 56 | US8791123, 55)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent