BDBM12760 1-(3-carbamimidoylphenyl)-N-{2-fluoro-4-[5-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]phenyl}-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::pyrazole analog 3i

SMILES NC(=N)c1cccc(c1)-n1nc(cc1C(=O)Nc1ccc(cc1F)-n1cnc2cc(ccc12)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LBFYGRDPTBUEKV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12760   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12760(1-(3-carbamimidoylphenyl)-N-{2-fluoro-4-[5-(triflu...)
Affinity DataKi:  0.290nM ΔG°:  -12.9kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2007
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

LigandPNGBDBM12760(1-(3-carbamimidoylphenyl)-N-{2-fluoro-4-[5-(triflu...)
Affinity DataKi:  6.40nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2007
Entry Details Article
PubMed