BDBM12745 2-{6-[4-(2-methanesulfonylphenyl)phenyl]-7-oxo-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-1-yl}benzamide::dihydropyrazolopyridinone analogue 8b

SMILES CS(=O)(=O)c1ccccc1-c1ccc(cc1)N1CCc2c(nn(c2C1=O)-c1ccccc1C(N)=O)C(F)(F)F

InChI Key InChIKey=QLWWMHXUPONILX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12745   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12745(2-{6-[4-(2-methanesulfonylphenyl)phenyl]-7-oxo-3-(...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed