BDBM127315 US8791268, 26

SMILES CC(C(=O)NCc1ccc(nc1N1CCC(C)CC1)C(F)(F)F)c1cc(F)c(N)c(F)c1

InChI Key InChIKey=KOJARYJLVZXXMB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 127315   

LigandPNGBDBM127315(US8791268, 26)
Affinity DataKi:  3.40nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
Go to US Patent

LigandPNGBDBM127315(US8791268, 26)
Affinity DataKi:  9.60nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
Go to US Patent

LigandPNGBDBM127315(US8791268, 26)
Affinity DataKi:  9.60nMAssay Description:Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as reduction in capsaicin-induced intracellular calcium level preincubated for 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed