BDBM127314 US8791268, 18

SMILES CC(C(=O)NCc1ccc(nc1N1CCC(C)CC1)C(F)(F)F)c1ccc(NC(C)=O)c(F)c1

InChI Key InChIKey=HYBSWJLMINBBRB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127314   

LigandPNGBDBM127314(US8791268, 18)
Affinity DataKi:  25nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
Go to US Patent

LigandPNGBDBM127314(US8791268, 18)
Affinity DataKi:  25nMAssay Description:Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as reduction in capsaicin-induced intracellular calcium level preincubated for 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed