BDBM126911 US8785464, 70

SMILES COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(c(Oc2cccc(C)c2C#N)n1)C(F)(F)F

InChI Key InChIKey=HPMBFZIPRNMYPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126911   

TargetFocal adhesion kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126911(US8785464, 70)
Affinity DataIC50: 9nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
Go to US Patent